In a study of healthy adult men, growth-hormone secretion was reported to remain pulsatile during continuous stimulation by the long-acting GHRH analog CJC-1295, while trough and mean GH concentrations were observed to increase.
CJC-1295
A modified version of a hormone signal, studied in research on growth hormone and IGF-1.
The short version
A modified version of a hormone signal, studied in research on growth hormone and IGF-1.
What does the research tell us?
A result in a cell or an animal does not establish the same result in people. Read the study design, the measurements, and the limitations before drawing a conclusion.
What remains uncertain?
The research question, the formulation, and the population all matter. This page is a starting point for understanding the literature, not a complete assessment of benefits or risks.
Identity & technical details
For readers who want the reference details.
- Name
- CJC-1295
- Also known as
- Modified GRF (1-29)
- Topic
- Hormone signalling
- CAS
- 446262-90-4
- Amino-acid sequence
- YADAIFTNSYRKVLGQLSARKLLQDIMSR
Explore the sources
Open a source to read its methods and limitations. Published titles are kept in their original language.
Using two-dimensional gel electrophoresis on serum from normal adult subjects, this study characterized serum protein-profile changes associated with administration of the long-acting GHRH analog CJC-1295 and proposed candidate serum proteins as markers of GH/IGF-1 axis activity.
This analytical-chemistry report describes the identification of CJC-1295 in an unknown pharmaceutical preparation; using mass spectrometry the authors characterized a 29-amino-acid, C-terminally amidated peptide whose sequence is consistent with the GHRH analogue.
A qualitative netnographic study analyzing online discussion-forum content documents how some women who report self-administering the GHRH analogue CJC-1295 discuss sourcing, administration practices, and self-reported effects. The paper documents user-reported accounts and online discourse; it does not test the compound clinically and makes no safety or efficacy claim.
This guide explains research. It does not recommend a treatment, product, or dose.
A laboratory arithmetic tool. It does not determine a dose for a person.
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